GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs9902453 | 1 | rs4328498 | chr17:28344276 | CORO6 | chr17:27941774-27948441:- | -0.5 | -11.58 | 1.65E-27 | Coffee consumption (cups per day) |
| THCA | cis | rs9902453 | 1 | rs4328498 | chr17:28344276 | EFCAB5 | chr17:28256874-28435469:+ | -0.59 | -11.22 | 4.19E-26 | Coffee consumption (cups per day) |
| THCA | cis | rs9902453 | 1 | rs4328498 | chr17:28344276 | GIT1 | chr17:27900487-27916610:- | -0.29 | -6.75 | 4.24E-11 | Coffee consumption (cups per day) |
| THCA | cis | rs9902453 | 1 | rs4328498 | chr17:28344276 | LRRC37B2 | chr17:28903483-28992715:+ | -0.17 | -3.8 | 0.000161 | Coffee consumption (cups per day) |
| THCA | cis | rs9902453 | 1 | rs4328498 | chr17:28344276 | SSH2 | chr17:27952965-28257018:- | -0.34 | -7.56 | 2.12E-13 | Coffee consumption (cups per day) |
| THCA | cis | rs9902453 | 1 | rs4328498 | chr17:28344276 | TP53I13 | chr17:27895739-27900174:+ | -0.2 | -5.41 | 9.75E-8 | Coffee consumption (cups per day) |
| THCA | cis | rs59374417 | 1 | rs4330287 | chr3:119288848 | ADPRH | chr3:119298523-119308791:+ | -0.21 | -3.47 | 0.000565 | Vitiligo |
| THCA | cis | rs4332428 | 1 | rs4332428 | chr10:4965434 | AKR1C2 | chr10:4964715-5060207:- | 0.3 | 3.98 | 8.11E-5 | Height |
| THCA | cis | rs7027110 | 1 | rs4333673 | chr9:109610456 | ZNF462 | chr9:109625378-109773789:+ | -0.12 | -3.9 | 0.000112 | Height |
| THCA | cis | rs1926657 | 1 | rs4334136 | chr13:95866778 | ABCC4 | chr13:95672084-95953687:- | -0.19 | -3.64 | 0.000303 | Breast cancer |
| THCA | cis | rs10935120 | 1 | rs4334685 | chr3:134304335 | ANAPC13 | chr3:134196547-134204865:- | 0.37 | 11.48 | 4.06E-27 | Height |
| THCA | cis | rs10935120 | 1 | rs4334685 | chr3:134304335 | CEP63 | chr3:134204575-134293852:+ | 0.3 | 6.4 | 3.75E-10 | Height |
| THCA | cis | rs726288 | 1 | rs4335481 | chr10:81733840 | LOC219347 | chr10:81805991-81838949:- | 0.51 | 5.21 | 2.88E-7 | Rheumatoid arthritis |
| THCA | cis | rs433598 | 1 | rs433598 | chr16:20680206 | ACSM1 | chr16:20634559-20709066:- | 0.54 | 11.33 | 1.6E-26 | Schizophrenia |
| THCA | cis | rs433598 | 1 | rs433598 | chr16:20680206 | ACSM3 | chr16:20775312-20808478:+ | -0.18 | -3.45 | 0.000602 | Schizophrenia |